The story of the series "Paytakht 6" begins with the death of Baba Panj Ali and the donation of his organs. Behbood Fariba, after years, returns to Iran, but faces challenges that alienate Fahimeh from her husband. In this season, Behbood is afflicted with Restless Hand Syndrome. Behtash, who was unemployed and unstable in the previous season, is now the goalkeeper for Nassaji Mazandaran football club and is interested in football player Peter Czech. Naqi becomes politically active and serves as the driver and personal guard of a parliamentary representative. Homa, Naqi's wife, also becomes a news presenter. Arastoo unintentionally gets involved in drug trafficking with someone named Kavous and uses Naqi's car, the driver of the parliamentary representative, to transport drugs. Behtash, who shone as a goalkeeper for Nassaji, joins Panathinaikos in Greece.
On the other hand, Rahmat marries Mrs. Bayati. After these events, a year passes, and Homa's brother accuses Naqi of infecting their father with the coronavirus and causing his death. Arastoo, who was arrested for distributing drugs, is released and starts selling pants. Rahmat also becomes the father of triplets.